MASQUELIER's® OPCs & Leg Veins

The maintenance of normal and healthy circulation, which is critical for the functioning of the heart and all tissues in the human body, requires the return of blood by the veins from different parts of the body to the heart. The circulation of blood through leg veins requires an extra effort since the blood has to return to the heart against gravity. Leg veins contain a series of muscle-driven pumps and one-way valves that allow blood to flow in only one direction - upwards. Veins also have a high ratio of collagen to elastin. Collagen, along with glycoproteins, is essential for the maintenance of structure of the vein wall. The high level of collagen also provides tensile strength to the vein wall, and together with elastin, prevents excessive distension of the veins in response to the large volume of blood contained in them. These structural properties enable veins to better perform their function of ensuring that blood flow back to the heart is appropriately regulated.

Weakening of the vein walls and valves occurs due to various factors such as sitting or standing for long periods, age, smoking, pregnancy, oral contraceptives or a family history of varicose veins. As we age, and due to a more sedentary, less active lifestyle, this can result in a feeling of heaviness in the legs and occasional cramping, particularly nocturnal leg cramps.

There is strong scientific evidence that MASQUELIER's® OPCs strengthens blood vessels and maintains a healthy venous system, thereby reducing occasional cramping, heaviness and tingling in the legs. In several clinical studies, MASQUELIER’s® OPCs has been shown to have a beneficial effect on vein functional aspects such as venous tone and venous compliance, and to significantly reduce occasional leg cramps, heaviness, and tingling sensation. For instance, a large study was conducted in France involving 4729 female volunteers who exhibited heaviness, tingling sensation and cramps in legs following oral hormone intake (estrogen progesterone or progesterone only). The volunteers were advised to take MASQUELIER’s® OPCs for 90 days. At the end of 90 days, the physicians observed that the improvement in leg cramps, heaviness and tingling was excellent or good in 89.9 of volunteers and average or poor in 10.1 of the volunteers. The physicians concluded that MASQUELIER’s® OPCs is effective in improving and maintaining venous function, and is also safe.

The beneficial effects of MASQUELIER’s® OPCs on vein function are linked to its ability to bind collagen, elastin and glycosaminoglycans (key components in vein walls and vein valves), and promote collagen synthesis, protect collagen and elastin from degradation and regulate glycosaminoglycan levels. Through these actions, MASQUELIER’s® OPCs can greatly reinforce vein walls and vein valves, supporting their function in the body.